Researchers Manipulate Shape of Nanoparticles to Deliver Gene Therapy Without Viruses
Researchers from Johns Hopkins and Northwestern universities have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make a big difference in how well they work in treating cancer and other diseases.
This study is also noteworthy because this gene therapy technique does not use a virus to carry DNA into cells. Some gene therapy efforts that rely on viruses have posed health risks.
“These nanoparticles could become a safer and more effective delivery vehicle for gene therapy, targeting genetic diseases, cancer and other illnesses that can be treated with gene medicine,” said Hai-Quan Mao, an associate professor… in Johns Hopkins’ Whiting School of Engineering.
(via Shape coding replaces risky viruses in DNA nanoparticle therapy | KurzweilAI)