Bioprinting Researchers Overcome Key Obstacle to Printing Blood Vessels
Bioengineers are already working on creating and assembling single layers of cells that have direct access to nutrients and oxygen — a process known as “bioprinting.”
But creating a full-fledged array of new vessels remains a major hurdle. Fluidic pressure coursing through these tiny systems can push apart their structural seams, and many cell types can’t withstand the sheer force of 3D bioprinting.
So researchers at the University of Pennsylvania decided to try a little reverse engineering. Instead of printing and layering lots of tissue and leaving hollow channels to serve as the tissue’s vasculature, they designed 3D filament networks inside a mold shaped like a vasculature system. The mold and template simply had to be removed once the cells formed a solid tissue around them.
(via Researchers a step closer to ‘printing’ new blood vessels | Cutting Edge - CNET News)