Design of Scaffolds Used to Engineer Tissue Determines Success of Transplants
Tissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases. However, it has been unclear why some implants work better than others.
MIT researchers led by Elazer Edelman, a professor of Health Sciences and Technology, have now shown that implanted cells’ therapeutic properties depend on their shape, which is determined by the type of scaffold on which they are grown. The work could allow scientists to develop even more effective implants and also target many other diseases, including cancer.
Read more: http://www.laboratoryequipment.com/news/2012/08/scaffolds-determine-success-engineered-tissue